NEW YORK (Reuters Health)
Aug 28, 2006

Results of a new study suggest a strong association between first trimester exposure to non-steroidal anti-inflammatory drugs (NSAIDs) and congenital anomalies, particularly those related to cardiac septal closure. The five most commonly filled prescriptions were for naproxen (35%), ibuprofen (26%), rofecoxib (15%), diclofenac (9%), and celecoxib (9%).

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